One in three women with inconsolable babies reports feeling depressed, says research on nearly 3,000 new moms. "I see a lot of fussy babies," says researcher Pamela High, M.D., a clinical professor of pediatrics at Brown Medical School in Providence, R.I., "and the mothers are worried, anxious, tired and depressed." High's study is the first to establish a link between colic and postpartum depression in a demographically diverse group of women. She advises a new mom to recruit others to help, and to set aside time every day to be off-duty. "There's that saying that it takes a village," High says, "and I think that's true from the very beginning."