This Common Morning Sickness Drug May Not Be as Effective as We Thought

The research that touted the benefits of this popular morning sickness remedy may have been overstated, according to a new study. Should you still take it?

Morning Sickness Drug VGstockstudio/Shutterstock
Diclectin has been one of the commonly prescribed anti-morning sickness drugs out there—but according to recent research, the medication might not be as effective as we once thought. A new Canadian study suggests that previous research—which was conducted back in the 1970s—may have overstated the drug's effectiveness. 

"We found two main problems with the [unpublished] study. Data was missing for 31 percent of participants. There are questions about the integrity of the data," study author Nav Persaud, MD, said, according to a release for this research. "The approval and prescribing of this medication are based on this study. The decision to approve this medication should be revisited. The prescribing of the medication should be revisited." 

Dr. Persaud and his colleagues conducted this research by studying documents from the FDA, which led them to conclude that the methods used to measure the drug's effectiveness were unclear. According to Dr. Persaud and his team, many women surveyed did not complete the trial, which involved administration of a placebo and seven different morning sickness drugs (including Diclectin)—and the new study's authors claim just 14 percent of the women involved in the original study rated the drug as moderate or excellent in controlling morning sickness.

But is this research significant if you're using the drug and responding well to it? Not according to Mitchell Kramer, MD, chairman of obstetrics and gynecology at Northwell Health's Huntington Hospital, in New York. "Women prescribed Diclectin should not be worried," Dr. Kramer said, according to HealthDay.  "The comments about the study are of no value. They will not alter my use of Diclectin, nor would I recommend people use this critique as a guideline."

Most women don't end up on drugs like Diclectin unless they have severe morning sickness, like hyperemesis gravidarum. And while the jury seems to be out on its effectiveness overall, if it works for you, it sounds like you might still want to stick with it.

Have you had good luck with this particular drug?